The Science

Discover more information about how the Stabilized SulforaphaneTM in BrocEliteTM aids in detoxification from environmental toxins, supports a healthy immune system, reduces inflammation and supports cognitive function. 

All papers referenced are peer reviewed scientific research found on the National Institute of Health’s pubmed publications portal.

Sulforaphane promotes detoxification

Sulforaphane increases the antioxidant capacity of cells by two main mechanisms. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570035/

  1. Sulforaphane increases glutathione. (1)
  2. And it induces phase 2 detoxification enzymes. In fact, sulforaphane is the most potent chemical to induce phase 2 enzymes that has been identified. It acts by activating Nrf2 and ARE, and increasing glutathione S-transferases activity. (23, 4, 5, 6).
 

Sulforaphane supports a healthy immune system

Sulforaphane improves clearance of bacteria by macrophages and increases the activity of natural killer cells in mice (7).

Sulforaphane boosted the Th1 immunity in studies performed on aging mice.  It was also found to delay the reduction of cell-mediated immunity that occurs with age (8).

 

Sulforaphane reduces inflammation

Sulforaphane inactivates nuclear factor kappa-B (NF-κB), a key inducer of inflammation (9).

Sulforaphane also activates Nrf2, which lowers inflammation, and decreases proinflammatory mediators in mice (10, 11).

 

Sulforaphane protects the brain and restores cognitive function

Sulforaphane supports the longevity of existing neurons and encourages the formation of new neurons and synapses (12).

SFN reduces brain inflammation in various animal models of pathogen-induced neuroinflammation and neurodegenerative disease (1314, 15, 16).

 

Other Science

Effect of broccoli sprouts on insulin resistance in type 2 diabetic patients: a randomized double-blind clinical trial.

Potential efficacy of broccoli sprouts as a unique supplement for management of type 2 diabetes and its complications.

Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/dbT2DM mice

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation

Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition

The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention

Growth inhibition of a spectrum of bacterial and fungal pathogens by sulforaphane, an isothiocyanate product found in broccoli and other cruciferous vegetables.